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Angiogenesis is a critical step in the development and progression of solid tumors and is one of the most important prognostic factors. Identifying molecular markers of angiogenesis holds the promise of improving the clinical management of patients with tumors. Activated growth factors can trigger angiogenesis through the production of angiogenic factors. Multiple signaling pathways and transcription factors are regulated by these factors, and different combinations of these can give rise to different degrees of angiogenesis and a variable prognosis in the same tumor. Vascular endothelial growth factor (VEGF) and its receptors, platelet-derived growth factor (PDGF), basic fibroblast growth factor (bFGF), and transforming growth factor beta (TGFbeta), and matrix metalloproteinases (MMPs) have been implicated in many different aspects of angiogenesis. This brief review discusses the biologic behavior and activation of different angiogenic factors and their potential as targets for specific anticancer therapies.Harelyn Sawh, from Little Rock, Arkansas, has been in the US for nine years and said she has never felt welcomed by Americans,

When she told people she was from Haiti, she said people assumed she had never learned English.

“I think that I would have to teach people how to love” her, she said.

“I think that I would have to teach them how to forgive because they haven’t done much to have love given to them, too.”

The 19-year-old said she had no idea when she arrived in the US that racism was such a big problem.

“It’s very hard to see, especially when I’m with my family, where there’s always this